Glioblastoma is the most usual and aggressive tumor of  Trim 14 the nervous system. Despite stretched usage with confederated multiagent chemotherapy and surgery, patients generally show lean prognosis and remediless backslider of the malady . The intermediate survival time of patients with glioblastoma is short, at approximately 14.6 months . Therefore, effective identification and unfolding of modern molecular come to the diagnosis, usage and prognosis of patients with glioblastoma remain urgent clinical requirements.

Fifty two GBM tissue specimens were hold by the Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University. Ten normal brain tissues were collected as a negative control from patients experience decompressive craniotomy for vulnerary brain evil in the First Affiliated Hospital of Nanjing Medical University. 

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